Kaneka QH Ubiquinol and Cardio Health

June 2015, Xtend-Life Expert


CoEnzymeQ10 (CoQ10) is known as an essential nutrient that helps support the immune system’s response to oxidative stress. It also helps the body produce the majority (up to 95 percent) of its energy by converting the energy we take in through carbohydratess and fats into adenosine triphosphate (ATP), the molecule that serves as the bank for all our body’s energy stores.

CoEnzymeQ10 (CoQ10) is known as an essential nutrient that helps support the immune system’s response to oxidative stress. It also helps the body produce the majority (up to 95 percent) of its energy by converting the energy we take in through carbohydrates and fats into adenosine triphosphate (ATP), the molecule that serves as the bank for all our body’s energy stores.

“Despite the aging process, every cell in the body is in the business of producing energy to keep you vital and healthy. The energy each cell produces is in the form of a molecule called ATP, which is made in the energy powerhouse of the cell known as the mitochondria. Ubiquinol may help support the healthy energy production and processes within the body,” according to Dr. Mehmet Oz. (Ref. 1)

The heart requires a large amount of energy to expand and contract, and while the body is able to produce CoQ10 – so it can turn carbohydrates and fats into energy for our hearts to use - our ability to produce the enzyme goes down as we age, so after 40, we tend to have less of the nutrient on hand than we need.

Ubiquinol vs. ubiquinone: A tutorial

CoQ10 exists in the body in two forms – ubiquinone or ubiquinol. As we age, it’s not only harder to replenish the levels of CoQ10 we need, but also harder to convert existing ubiquinone to the more potent form, ubiquinol, so our bodies can use it better.  (Ref. 2)

That’s not good news when it comes to heart disease, because the heart – as our most powerful muscle requiring the most energy - is particularly vulnerable to those low levels of ubiquninol.

Studies have shown that people with heart conditions tend to have a significantly lower concentration of CoQ10 in their heart tissue than those without heart issues.

“I’ve often said I wouldn't practice cardiology without coenzyme Q10,” said Dr. Stephen Sinatra, who formerly served as the chief of cardiology at Manchester Memorial Hospital and founded the New England Heart & Longevity Center. “If there is just one thing you do to help maintain your heart’s health, make sure you’re taking CoQ10 daily.”

A 2008 study in the journal Biofactors, from longtime ubiquinol researcher’s doctors Peter H. and Alena M. Langsjoen found that supplementing with ubiquinol helped support and maintain healthy cardiovascular function.

In 2010, German researchers found that ubiquinol was also beneficial at helping maintain healthy cholesterol levels in a study that appeared in the Journal Molecular Nutrition and Food Research. (Ref. 3)


What about statins

Statins – the top-selling medications in the world – can be particularly damaging to ubiquinol levels.

Prescribed to help lower cholesterol, the drugs also have a tendency to lower CoQ10 levels, creating a serious catch-22 given that both high cholesterol and low CoQ10 are linked to heart disease.

According to a study appearing in the Journal of the American Medical Association, those who took the statin simvastatin showed a 22 percent decrease in ubiquinol levels in both the body and the heart muscle.

The study concluded that long-term use of statin medications can lead to nerve damage and breakdown of muscle tissue, which can lead to debilitating muscle pain. (Ref. 4)

We include genuine Kaneka QH ubiquinol in our Omega 3/QH Ultra. This is produced in Japan by Kaneka. Not only is Kaneka a world leader in ubiquinol research, but Kaneka is the first company to make ubiquinol available as a supplement.


  1. http://www.doctoroz.com/article/ubiquinol-ally-against-aging?page=1
  2. http://www.bodybuilding.com/fun/coq10-ubiquinone-ubiquinol-whats-the-difference.htm
  3. http://www.ncbi.nlm.nih.gov/pubmed/19096107
  4. http://www.ncbi.nlm.nih.gov/pubmed/19960455



    J DOVALL - June 16 2015

  • “Hi Robert, Thank you for your comment. At this stage, we have no plans for a placenta supplement. However, I will pass your feedback on to our team here. Please contact us at customer.service@xtend-life.com if you have any further questions or if you would like assistance with product recommendations. In good health, Madelynn”

    Xtend-Life Expert - June 17 2015

  • “Hi Samantha, Thank you for your comment. The amount of CoQ10 required really depends on the form used. We add 50mg of Ubiquinol in our Omega-3/QH Ultra which is far more effective than the oxidised form Ubiquinone. As the body easily recognizes Ubiquinol it is better utilized and less is needed for a significant effect. If you had a particular concern that requires additional CoQ10 support, you may like to take double the dosage of Omega-3/QH Ultra. However, for most, the amount in our standard dosage is very effective, with many noticing benefits within the first month. In good health, Madelynn”

    Xtend-Life Expert - June 17 2015

  • “How much does one require CoQ10?”

    Samantha - June 17 2015

  • “I am a type 1 diabetic, on the insulin pump.  I would like to take the ubiquinol supplement but I have a slight problem taking fish oils.  I have tried 4 different times over a period of 20 years to take a fish oil supplement and have found that this forced me to increase the amount of insulin to take.  My endocrinologist and my naturopath doctor cannot explain why this happens.  I don’t want to increase the amount of insulin so is there another form of ubiquinol available that I may take?  Being diabetic and with heart disease in my family, this supplement should be added to my daily routine somehow.”

    Kathy - August 25 2015

  • “Hi J Dovall, Thank you for your comment. We do not sell Ubiquinol on its own as it is required to be in an oil-emulsion to prevent it from getting oxidized and converted into Ubiquinone. Taking Ubiquinol in our fish oil blend also enhances the cardiovascular supporting effects of the antioxidant for better results overall. In good health, Madelynn”

    Xtend-Life Expert - June 17 2015

  • “I am from Indonesia. In USA market I see Liquid CoQ10, 100% Natural CoQ10. Is it really different between liquid and tablet (i.e: CoQ10). Thank you. ”

    Jim - February 28 2017

  • “Hi, im from malaysia, Just wander will xtend-life have Placenta supplement product… and what’s your take on it… in Malaysia have few brand from cheapest 55$ all the way up to a epic 330$ a month… ”

    Robert - June 04 2015

  • “Hi Jim, Thank you for your question. I have seen quite a number of ‘Natural CoQ10’ Liquid Supplements on the market. However, the main contributor to CoQ10’s efficacy is not whether it is in liquid or tablet form, but more the type of CoQ10 in the product. Majority of liquid CoQ10 supplements contain the Ubiquinone form instead of Ubiquinol. This is not as effective for the body to use, as the body mainly stores and uses Ubiquinol. You will be find out which form of CoQ10 a supplement contains on their product label. I would strongly suggest getting the Ubiquinol form of CoQ10. Our Omega 3 QH Ultra contains this, but we have gone a step further and sourced it from the ‘father’ of Ubiquinol which is Kaneka. You would not need large quantities of Ubiquinol CoQ10 because it is extremely effective, and when taken with fish oil it produces better benefits. If you have any other questions about CoQ10, I advise you to contact us at customer.service@xtend-life.com. Our team would be happy to assist you. In good health, Madelynn”

    Xtend-Life Expert - March 03 2017

  • “Hi Kathy, Thank you for your comment. I am sorry to hear that you have trouble with your insulin when taking fish oil. Unfortunately, Ubiquinol is extremely sensitive to oxidization and that is why top quality Ubiquinol products are in oil emulsions to protect the nutrient as well as enhance absorption. However, if you would like the benefits of CoQ10, you can take it in Ubiquinone form. It is not as effective as Ubiquinol but you should still be able to get some benefit from it. We have CoQ10 in Ubiquinone form in our Cardio-Support (which is in tablet form). We use Ubiquinone because it is the better form for tablets, wheras Ubiquinol needs to be in oil. Cardio-Support is a fantastic product to take for cardiovascular health and prevention against heart disease, and you may find it better for you since you are unable to get cardiovascular support from our fish oil. I hope this helps Kathy. Please contact our customer service team at customer.service@xtend-life.com if you require assistance with placing an order. In good health, Madelynn”

    Xtend-Life Expert - August 25 2015

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