Joint Replacement Metal Toxicity

Recently I have had an enquiry from a customer regarding potential chelation for heavy metal contamination due to metal joint replacements. I thought this information would be good to share to you all for general advice and interest.

The enquiry was regarding Chromium and Cobalt prosthesis, but the information is equally relevant to other metal alloys....

Hip prostheses are made from orthopaedic metal alloys, specially produced for fabrication of artificial joints. The Cobalt-Chrome alloys tend to contain the base metals cobalt (> 34%) and chrome (>19%) mixed with smaller quantities of other metals, even nickel.

With Titanium alloys the base metal is titanium of course, commercially used with 4% aluminium.

Stainless Steel alloys are base metal is iron (> 58%), mixed with larger quantities of chrome and nickel and some other metals.

Titanium is the best tolerated form by bone tissue however.

Metallic alloys used for fabrication of artificial joints do have the potential for corrosion when in contact with body fluids. Although the orthopedic alloys are very resistant to corrosion, their surface dissolves and the dissolved metals enter the circulation.

The metallic ions of these metals (Cobalt, Chromium, Nickel, but also the relatively inert Titanium) may combine with proteins in the body and trigger allergic immune responses. One such allergy reaction is skin rash, for example. The concentration of the metals in the blood can increase with time.

The most likely circumstances for corrosion, and hence release of metal alloy into the bloodstream, occurs either when two dissimilar metals are in contact. So if your hip replacement is ALL cobalt-chrome corrosion would be more likely to be minimal, and hence less harmful to health. However, if, say, the ball is made from Cobalt-Chrome and the stem from Titanium alloy, the corrosion may be at a higher rate, as these two metals can reaction with one another, and metal release into the system may be higher.

This can also be the case on metal-on-metal total hip joints, which may wear faster with production of many small particles of metal alloys. These small particles can corrode and dissolve in the body fluids.

Trace-metals Cobalt and Chromium are a part of body's enzyme system, and there is no proof that elevated serum levels of Cobalt, Chrome, or Titanium produce pathological changes in hip replacement patients. However this is a relatively unstudied area. Therefore the question of the long-term effects of orthopedic metals (Cobalt, Chromium, and Titanium) on patients with total hip replacement is still not fully known.

Chromium and Cobalt are excreted by kidneys. Therefore unless you have impaired renal function the blood concentrations of these metals are likely to be low and not worrying in terms of general health.

If you feel you have a concern with regards to heavy metal corrosion of a metal joint replacement, the first advice would be to have some simple blood tests to test for any levels, and importantly what these levels are. This will give you more information as to whether you have reason to consider further treatment specific to actual chelation. Depending on the results, different levels or metals involved may result in different advice for treatment, conventionally and naturally.

In the meantime, it is a good idea to protect your immune system, both due to the potential reaction sensitivity mentioned above, and also to help protect against any such relating health issues.

I would choose our Total Balance Premium and ranges for general health protection and enhancement. I would also consider adding to help with immune system enhancement more specifically if you are a joint replacement patient.

Ensure that your general health, diet and fluids, is also as healthy and optimal as possible to give your body the best resistance to degenerative disease.

17 Responses

Dear Sir,I am extremely interested in your comments on the potential effects of Titanium hip replacement components especially the potential problem of degeneration of bone structure when in contact with the insertion of the ball and pin in the leg bone and the cup.
It appears from your comments that it is quite possible that there can be a rejection of the colbalt residues with the bone and a lesser reaction with chrome alloys causing degeneration of the bone and and a loosening of the stem eventially necessitating a second replacement.

I will give you a brief review of my experience.
Total hip replacememt 2001, Composite cup and titanium ball and stem.Because of the degeneration of bone arround the stem I have had 1st June 2011 replacement of lengthened ball and stem, degenerated bone removed (top thick nob) plate screwed to new stem and bone graft, a reconstruction taking 4.5 Health Waikato N Z.There is no degeneration of the cup and it was considered that wear of the cup was minimal and it was not replaced.
My second hip was replaced with a similar operation 2003 and has had exactly the same degenaration as the first and I am due for the same operation as I recently had.
I am certain that my experience is a result of cobalt residues causing bone degeneration.

I am now deciding what I should do to research this and what measures should be taken to remedy a similar occurance in my new replacement or should there be a different material used for my next operation 2 mths time. R.J.Jackson

R.J.Jackson June 26 2011

Hi Ringo,

It may be possible that at least some of your mum’s symptoms are due to metal toxicity, and it could be from her hip. But of course we cannot diagnose this as we can’t test or investigate it, as i am sure you can understand. So if you believe this it is essential to persevere with the hospital and doctors to find out what type of metals were involved (it is possible for it to be traced, but highly unusual for this information not to be recorded in the first place), and to find a doctor, or naturopath who can test for metals in the blood. This is certainly the root i would take to confirm what the problem causes are so that she can be treated correctly.

In the meantime, it may help her to take our Total Balance, Omega 3/DHA, and even Kiwi-Klenz, for example, to try to help with her general health and balance, and her body’s optimal ability to deal with imbalances itself.

Depending on what medications she is on, Cardio-Klenz could also be helpful for her cardio health; and Viral-Protec to try to help deal with and prevent any infections and boost the immune system.

I hope this helps.

Xtend-Life Expert June 29 2012

 I have my knee replacement (both knees) in September 2011 and my question is:  Is it possible to use this product EDTA Creme?  I received my order already on this product.  I used it for about 4 days now and I feel some heaviness on my knees and a little pain when I walk.  Will you please tell me if its possible to use this product.  Appreciate your help and your input on this matter.  Thank you!

Alefa Butler March 01 2013

What are your thoughts on Chelation treatment.I have read & heard that it is unproven?



Gordonc April 23 2011

i have had a cervical metal plate with screws in my upper spine. is this the same idea?

Xtend-Life Expert April 22 2011

Dea Xtend Life,

I have an inquiry to make, and that is my brother had done a heart scan and was found that he has about 20 Calcium blocks as what was said by his doctor. He refuses to go for any of the therapies where even a needle could be used. So I had suggested to him to use your Cardio Klenz which we bought from you and he has been taking it very regularly for the last one month and what I like to know if this would help clear all the calcium blocks eventually or is there some other products that he has to take. He is 69 years old. Please advice. Please keep this Confidential.

Syed April 22 2011

Hi Gordonc,

Chelation therapy is the administration of chelating agents to remove heavy metals from the body. So this could mean many different forms. For example, there are chelation ingredients in our Cardio-Klenz that help clean the arteries, and these work. There are other ingredients, such as EDTA, which can also work, but only when administered in a particular way. In the case of EDTA, it needs to be by subcutaneous injection in order to have any real effect, therefore under the direction of a GP, and if this is necessary depending on the nature, metal type, and severity of the problem.

So chelation does work, as is proven by the success we have with Cardio-Klenz, for example. But there are many types of chelation and it is important that certain ingredients are administered in a particular way, and in a specific combination that suits their needs, and the needs and severity of the patient.

Xtend-Life Expert June 27 2011

I have a replacement knee (2001) which is as far as I know made of stainless steel, can you tell me if this can cause the same problems as the hip replacement.

John March 14 2012

Hi Maria,

As these are just screws and are single items rather than mixed metal joint formations, this shouldn’t be a problem. However, as you have had toxicity in the past, it would be a general good idea to try to help protect your immune system as much as possible as a general preventative aid.

Xtend-Life Expert June 27 2011

Hi Debra,

Apologies first of all for the delay in response. I hope this hasn’t been inconvenient for you.

Any joint or bone replacement could be relevant, it depends on the type and mixture of metals. If you are unsure, or cannot find this information out, you could take the improvements steps as a good measure to try to help prevent any problems, for example.

Xtend-Life Expert June 27 2011

Hi RJ,

Thanks for your comments on your experience. This seems like a good potential example of what can happen, yes. The best thing i can advise is to perhaps discuss the concerns with your doctor in terms of finding out if it is available in your area to have like-for-like metal components inserted, i.e. not metals that may react with one another, as appears to have been the case here. It isn’t always possible in all areas, and some doctors may have to work with what is available to them. But it is certainly worth checking out what you can do in your area.

In the meantime, perhaps consider a protocol such as I suggested in order to try to help your bone degeneration and immunity in the meantime and near future. As you have had bone degeneration directly, I would also perhaps advise taking a look at our Bone-Protec for the purpose of trying to help improve and keep the quality of bone formation that you do have.

I hope this helps.

Xtend-Life Expert June 27 2011

Hi John

If it falls into the same categories as laid out for the hip replacement metals then the same references may apply.

Xtend-Life Expert March 14 2012

Hello Lauri, I am glad to hear that you found our article interesting. The symptoms that you have been experiencing dont sound much fun at all. But as we arent medical professionals I advise you to seek the guidance of an expert in the area of heavy metal toxicity. Perhaps the professional that provided your sample analysis would be a good place to start. They should be able to refer you to a naturopath or other suitably qualified person to advise you on chelation therapy. We are more than happy to speak with you regarding the various products in our range that may be beneficial for your needs. We are just a call away, or you can reach us at In good health, Rose.

CustomerRelations October 24 2017

Hello, I haven’t had a hip replacement – however, I do have 4 dental crowns in my mouth (for the last 35 years) that likely contain cobalt and nickel. Hair sample analysis shows levels high in 1990 and currently in 2017. Does anyone have anything to share regarding the safe removal and/chelation of cobalt and nickel? Quite frankly, I’m really scared. Right now I’m experiencing insomnia, dermatitis, low thyroid, heart palpitations, and celiac disease. Thank you for anything you can share!

Lauri October 20 2017

I had a lot of metal toxicity when I was younger. I have had brain surgery and have some titanium screws in my head. Would this be a problem too?

Maria April 22 2011

Hi Syed,

Cardio-Klenz is a good product to use and this may help to improve his arterial health and blockages, yes. Ideally I would include with this Omega 3/QH Ultra, to try to help further with cardio health, strength, and general blood flow. This may help further. Ensure of course that his diet, fluid intake, and daily exercise regime are all as optimal and healthy as possible. This is equally important. And ensure regular re-evaluations of his health status, so he knows how he is progressing in case he needs further help.

Xtend-Life Expert June 27 2011

Can anyone please throw any light on our problem
my mum now in her 80s but has been very active up to recently .

had a hip replacement done in 2006 and had problems with it being loose a short time after it was put in.
she had siatic pain all the time as well.

but last year she became unwell and breathless and was diagonsed with a faulty heart valve .
The keyhole operation was carried out and all seemed well until the next day and needed to be rushed to the theater again to have a pacemaker fitted because the heart beat was not correct.
Things were better then for a while but the tiredness got worse.
after many blood tests and investigations there couldnt be any reason found what was causing the weight loss and muscle tone failure of course they are still checking .
but upon reading some blogs on the internet i feel that the problems are comming from her metal on metal hip replacement.
it is not the apy hip that there is lots of info about but i cant find out from the hospital in england what metals are in the hip used .

her doctor is in the dark about any blood tests available to test for metals in the blood .
i cannot believe that there isnt information available to local gps in this day and age but it is happening in small towns all over northern Ireland and im sure else where too.
even when the doctor looks for information from the hospital where the hip was fitted the information is not available.
it seems that the medical profession are twidling their thumbs while my mums health is getting much worse.
i feel that she has metal poisoning
her tongue is blue and she tastes metal every morning.

i dont know where to turn next.
i saw someone on a blog ask for a consultation with a metal rejection specialist in oxford.
if anyone knows the contact number so i can talk with this person for advice i would be grateful thanks .

Ringo Mc James June 21 2012

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