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Health Benefits and Uses of Huperzine A

Brain Health Support


Huperzine A Background and Benefits

huperzine-aHuperzia serrata, previously known as Lycopodium serratum, is a type of clubmoss. Its common names include Chinese Club Moss and toothed clubmoss. This plant is also known as Jin Bu Huan and Qian Ceng Ta in Traditional Chinese Medicine (TCM). H. serrata is native to Southeast Asia, although it’s widely distributed throughout tropical climates with abundant rainfall.

The primary reason for H. serrata’s commercial value is that it contains a high level of huperzine A, a chemical classified as a sesquiterpene alkaloid. Other species of Huperzia also contain huperzine A, but in lower concentrations. Huperzine A inhibits the production of the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. It is also an antagonist of the neurotransmitter N-methyl-D-aspartic acid (NMDA) and can cross the blood-brain barrier.

Crude extracts of H. serrata have been used in TCM for centuries for a variety of purposes such as blood disorders, fever and unhealthy inflammation. The modern preparation of H. serrata extract involves significantly more processing, generally for the purpose of increasing the concentration of huperzine A. Huperzine A’s benefits as a health supplement primarily derives from its effect on acetylcholine levels in the brain. More studies on huperzine A are needed to determine its long-term effects.

Uses of Huperzine A

The most significant uses of huperzine A deal with the brain and nervous system. The benefits include support for cognitive and memory recall as well as support for the muscles and nervous system.

Cognitive support


Oral supplements of huperzine A may support mental function, according to some studies. The regimens in these studies were up to eight weeks in length.

Nervous system support

Huperzine A may support nervous system functions in the presence of organophosphates.

Body Diagram

Memory recall support


Some research shows that huperzine A may support memory in older children and teenagers. This research studied the effects of huperzine A for up to four weeks.

Muscle support


Huperzine A may help to manage muscle weakness caused by some aging conditions, according to some studies.

Signs You May Need Huperzine A

Cognitive impairments that affect memory and learning are the most common indications that you may need huperzine A supplements. These signs are especially significant when they are caused by age-related conditions. Additional signs that huperzine A may help you include chronic muscle weakness, fatigue and lack of alertness. Organophosphate poisoning is also an indication that you may need huperzine A, which is often caused by exposure to herbicides and insecticides.

Products containing Huperzine A

Neuro-Natural General

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Fuel for a healthy brain & nervous system

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Neuro-Natural Recall

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Support brain function and memory recall

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Neuro-Natural Serenity

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Fuel for a healthy nervous system & mood

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Neuro-Natural Sleep

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Supports healthy sleeping patterns

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Other Ingredients That May Be Of Interest

SAMe - S-adenosyl methionine is a cosubstrate with many common names such as SAMe, AdoMet and ademetionine. Its most important biochemical role is generally the transfer of methyl groups between chemical compounds. This function includes many specific reactions in the human body. Additional roles of SAMe involve the transfer of sulfur and propyl groups.

Vinpocetine - Vinpocetine is derived from vincamine, an alkaloid found in the lesser periwinkle plant. Its most common uses as a health supplement include support of the nervous system and maintaining healthy blood flow to the brain.

Synonyms and Similar Forms of Huperzine A

Chinese Club Moss, Toothed clubmoss, Jin Bu Huan, Qian Ceng Ta, H. serrata