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Health Benefits and Uses of DL-Phenylalanine

Pain Management


DL-Phenylalanine Background and Benefits

phenylalaninePhenylalanine is an amino acid that is commonly abbreviated as F or Phe. All phenylalanine molecules have the chemical formula C6H5CH2CH(NH2)COOH, although their exact structure may vary. Phenylalanine exists in two different forms, which are called D-phenylalanine and L-phenylalanine. These forms are known as enantiomers of phenylalanine, which are structural mirror images of each other. The structures of phenylalanine were established during the late 19th century, beginning in 1879.

L-phenylalanine is an essential amino acid, meaning that it is necessary for human life but can’t be synthesized in the body. The DNA codons for L-phenylalanine are UUC and UUU. L-phenylalanine is primarily used to synthesize proteins, although it also serves many biochemical functions directly. It has many dietary sources, especially meat and dairy products. Additional sources of L-phenylalanine include leafy green vegetables.

D-phenylalanine isn’t an essential nutrient, although it is one of the few D enantiomers of amino acids that are pharmacologically active. This activity is generally the result of inhibiting the action of enzymes. D-phenylalanine generally isn’t found in nature and is produced only in the laboratory.

A mixture of more than one enantiomer of the same chemical is known as a racemic mixture. Phenylalanine is commercially available in racemic form, which is commonly known as DL-Phenylalanine. Each enantiomer of phenylalanine provides separate health benefits.

Uses of DL-Phenylalanine

The health uses for DL- phenylalanine generally deal with its effect on neurotransmitters. Typical applications include the relief of discomfort, support of healthy energy levels and the management of stress.

Stress management


DL-phenylalanine may help to manage stress through its role in the production of norepinephrine.

Discomfort management


The management of discomfort is one of the most common uses of DL-phenylalanine. Researchers believe that the regulation of the endogenous analgesia system is the primary mechanism of this effect.

Body Diagram

Mood management


DL-phenylalanine may help to manage low moods by supplementing the effects of dopamine.

Energy support


Some research shows that DL-phenylalanine may support the production of neurotransmitters such as serotonin and dopamine. These chemicals help to maintain your normal energy levels.

Signs You May Need DL-Phenylalanine

Chronic discomfort is one of the most significant signs that you may need DL-phenylalanine supplements, especially when it’s the result of an infection or injury. Low energy levels and sleep disturbances are also an indication that you may benefit from DL-phenylalanine. Conditions that deplete the body’s natural supply of neurotransmitters may mean that you need DL-phenylalanine. These conditions include stress and the use of drugs such as caffeine and nicotine.

Products containing DL-Phenylalanine

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Other Ingredients That May Be Of Interest

L-threonine - Threonine an amino acid with the chemical formula HO2CCH(NH2)CH(OH)CH3. It is most common uses derive from its role as a precursor for glycine, which provides many neurological benefits.

5-HTP - 5-HTP and oxitriptan are common names for 5-hydroxytryptophan, which has various direct biological functions in the body. This amino acid is also the precursor for essential neurotransmitters, including melatonin and serotonin.

Synonyms and Similar Forms of DL-Phenylalanine

L-phenylalanine, D-phenylalanine